Extracellular HSP70 peptide complexes alter expression of Glut1 and VEGF in HepG 2 cells via HIF-1α
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چکیده
منابع مشابه
Expression and correlation of HIF-1α, MIF, COX-2 and VEGF in psoriasis lesions
Psoriasis is a common chronic, inflammatory and proliferative skin disease that is widely associated with multiple factors under a polygenic background. The expression of hypoxia-inducible factor-1α (HIF-1α), macrophage migration inhibitory factor (MIF), cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) is associated with psoriasis; however, there have been no systematic st...
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Hypoxia-inducible factor 1α (HIF-1α) and vascular endothelial growth factor (VEGF) play important roles in angiogenesis and tumor growth. Tanshinone IIA (T2A) is a novel antiangiogenic agent with promising antitumor effects; however, the molecular mechanism underlying the antiangiogenic effects of T2A remains unclear. In the present study, we provided evidence showing that T2A inhibited angioge...
متن کاملHIF-1α and GLUT1 gene expression is associated with chemoresistance of acute myeloid leukemia.
AIMS Much evidence suggests that increased glucose metabolism in tumor cells might contribute to the development of acquired chemoresistance. However, the molecular mechanisms are not fully clear. Therefore, we investigated a possible correlation of mRNA expression of HIF-1α and GLUT1 with chemoresistance in acute myeloid leukemia (AML). METHODS Bone marrow samples were obtained from newly di...
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ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2013
ISSN: 2219-2859
DOI: 10.11569/wcjd.v21.i36.4175